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Yeast Surface Display Analysis of α-Agglutinin System (Agα)

α-agglutinin is encoded by the Agα1 gene and has only one core subunit. 320 amino acid residues of its C-terminal (serine and threonine-rich support region and GPI anchor protein attachment signal region) are covalently bound to the cell wall glucan, making it anchored on the cell wall. The C-terminus of the target protein is fused with the N-terminus of α-agglutinin, and secreted and expressed under the guidance of signal peptide, thereby achieving display and expression of foreign proteins.

Yeast Surface Display Analysis of α-Agglutinin System-CD BioScience

Service introduction

Creative BioMart R&D center has accumulated many years of technical experience to provide customers with mature and efficient yeast surface display analysis of α-agglutinin system.

Features of yeast cell surface display technology

  • The expression bias is small.
  • The relative molecular mass range of fusion protein is wide.
  • The number of fusion protein molecules is large.
  • Convenient for screening, purification and activity determination.

Application of yeast surface display technology of α-agglutinin system

  • Directed evolution of protein
  • Screen mutants with high affinity, stability and activity to achieve directed evolution of the target protein.

  • Draw an epitope map
  • Identify the residues that interact with proteins.

  • Antibody detection and screening
  • Prepare specific antiserum and polyclonal antibodies.

  • New drug screening
  • Clarify the targets of some drugs, and screen new drug lead compounds/peptide drugs for the treatment of the disease.

Service process

Please let us know the details of your yeast related projects through online consultation. We will reply to you in time and provide you with a comprehensive evaluation report on your project, including the feasibility evaluation of the project and the detailed experimental plan designed by our professionals. As our condition optimization is completed, the result report and other final products will be delivered to you immediately.

Yeast Surface Display Analysis of α-Agglutinin System-CD BioScience

Creative BioMart has accumulated many years of experience in the field of yeast research, helping our customers accelerate research in all fields using yeast as a research tool, and improve the overall success rate of the project. Please tell us your project requirements, and we will provide you with a full service from strategy design to final report. If you have any questions, please feel free to contact us.