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Yeast Library Construction Service for Transcription Factors

Yeast Library Construction Service for Transcription Factors

Transcription factors are the key components to achieve gene expression regulation and participate in every aspect of plant growth and development. In eukaryotes, about 5% of genes encode transcription factors, and about 50% are plant-specific transcription factors.

In the process of screening yeast single-hybrid cDNA libraries, customers often encounter unsuccessful screening of desired transcription factors. Because of this, Creative BioMart has compiled a database of transcription factors from multiple species and established a transcription factor-centric technology to identify its recognition elements. This technology can accurately, quickly, simply and efficiently identify the elements recognized by transcription factors, and has broad application prospects in the study of interactions between proteins and DNA elements.

The experimental principle of the system is to introduce the method of sequence randomization to construct a random DNA library, and then use the yeast one-hybrid technology to screen the library to identify the DNA sequence that specifically binds to the transcription factor. The transcription factor studied is Bait, and a random short DNA sequence library is cloned into the pHIS2 vector as Prey. One element sequence is enough to bind to TF.

Service introduction

Creative BioMart combines many years of experience in yeast related research to provide yeast library construction service for transcription factors, which has great advantages in technology and quality.

Material requirements

  • Cell sample > 1*107
  • Animal sample > 1 g
  • Plant samples > 2 g
  • Total RNA > 500 μg

Delivery result

  • Experiment report, including experimental equipment, reagents, methods, experimental steps, experimental results, experimental conclusions.
  • Bacterial liquid or plasmids

Project cycle

It takes about 20 working days to complete yeast library construction service for transcription factors.

Service process

Please let us know the details of your yeast related projects through online consultation. We will reply to you in time and provide you with a comprehensive evaluation report on your project, including the feasibility evaluation of the project and the detailed experimental plan designed by our professionals. As our condition optimization is completed, the result report and other final products will be delivered to you immediately.

Yeast Library Construction Service Process for Transcription Factors -Creative BioMart

Creative BioMart has accumulated many years of experience in the field of yeast research, helping our customers accelerate research in all fields using yeast as a research tool, and improve the overall success rate of the project. Please tell us your project requirements, and we will provide you with a full service from strategy design to final report. If you have any questions, please feel free to contact us.