Yeast ATAC - seq Analysis

ATAC-seq (full name: Assay for Transposase-Accessible Chromatin with high throughput sequencing) is an innovative epigenetic research technique for the analysis of transposase-accessible nuclear chromatin regions by using high-throughput sequencing. This technique uses transposases to cleave open nuclear chromatin regions at a specific spatial and temporal location to obtain the regulatory sequences of all active transcripts in the genome at that specific spatial and temporal location. Eukaryotic cells assemble chromatin by folding genomic DNA with histones at different levels, and this precision assembly information plays a decisive role in the regulation of gene transcription.

The accessibility of chromatin regions is a prerequisite for the interaction of specific trans-acting factors and cis-regulatory elements, and abnormal gene expression or alteration of chromatin regulators will have profound effects on the fate of cells, which in turn will lead to the onset and development of various diseases. ATAC-seq technology can be applied to all eukaryotic reprogramming studies, and is a new generation of beneficial tools for the study of major disease pathogenesis, drug mechanism of action, new drug development and biomarker function in the medical field.

Service introduction

Creative BioMart offers ATAC-seq services for yeast based on our strong Yeast Technology Center platform. Combined with powerful biochemical analysis capabilities, Creative BioMart not only provides massive amounts of sequencing data, but can also mine and refine useful results and publication quality images targeted to your research goals. Please contact us if you have a need in this area.

Provided by clients

• Yeast cell number ≥ 5 × 10⁷
• Yeast ≥ 200 mg (dry weight)
• Sample information sheet (the source, content, status and other basic information of the sample).
• Sample transportation

The sample is placed in a 1.5 mL centrifuge tube, sealed with parafilm, and shipped on dry ice.

Delivery content

Creative BioMart will provide you with detailed technical reports including:

• Experimental procedure
• Bioinformatics analysis results
• Display image of analysis results
• Raw data

Project cycle

• The operating cycle of the standard process is 45 working days.

Technical advantages

• Fast 

Streamlined experimental process and shorter delivery time

• Microvolume 

Low cell volume required (down to a few hundred cells)

• Comprehensive 

Large amount of information obtained (genome-wide regulatory activity profiles, full transcription factor binding profiles)

• Excellent value

Relying on the powerful experimental and sequencing strength of Yeast Technology Center platform, it has super cost-effective.

• Professional bioinformatics analysis

We have a professional bioinformatics analysis team to help customers conduct comprehensive mining of experimental data.

Service process

Why choose us?

With the advanced yeast center technology platform, Creative BioMart is committed to providing customers with a full range of yeast - related research service support and services. Please tell us your project requirements, and we will provide you with a full service from strategy design to final report. If you have any questions, please feel free to contact us.